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At the cellular level, vitamin B12 is involved in DNA synthesis and neuroprotection, acting as a cofactor for enzymes critical to these processes, such as methionine synthase and methylmalonyl-CoA mutase (72, 73)

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PINK1 (Figure 4D) and Parkin (Figure 4E) levels were decreased following CCl4 intoxication, whereas SAG administration significantly increased their levels